{"id":7649,"date":"2022-01-15T16:02:09","date_gmt":"2022-01-15T21:02:09","guid":{"rendered":"https:\/\/harmonipt.com\/?page_id=7649"},"modified":"2022-02-01T12:42:05","modified_gmt":"2022-02-01T17:42:05","slug":"why-offer-harmony-the-ispd-and-acmg-call-for-nipt-cfdna","status":"publish","type":"page","link":"https:\/\/harmonipt.com\/fa\/why-offer-harmony-the-ispd-and-acmg-call-for-nipt-cfdna\/","title":{"rendered":"\u0686\u0631\u0627 \u0647\u0627\u0631\u0645\u0648\u0646\u06cc \u0631\u0627 \u067e\u06cc\u0634\u0646\u0647\u0627\u062f \u06a9\u0646\u06cc\u0645\u061f \u0641\u0631\u0627\u062e\u0648\u0627\u0646 ISPD \u0648 ACMG \u0628\u0631\u0627\u06cc \u0627\u0646\u062c\u0627\u0645 \u062a\u0633\u062a NIPT cfDNA"},"content":{"rendered":"
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\u0648\u06cc\u062f\u0626\u0648 Ron Wapner \u06cc\u06a9\u06cc \u0627\u0632 \u0646\u0648\u06cc\u0633\u0646\u062f\u06af\u0627\u0646 \u0645\u0637\u0627\u0644\u0639\u0647 next \u0631\u0627 \u062a\u0645\u0627\u0634\u0627 \u06a9\u0646\u06cc\u062f<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div>

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2. \u0631\u06cc\u0632\u062d\u0630\u0641 22q11.2\u00a0<\/b><\/h2>\n

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\u0628\u0627\u0631\u062f\u0627\u0631\u06cc \u0647\u0627\u06cc \u062f\u0648\u0642\u0644\u0648<\/b><\/h2>\n

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\u0633\u0646\u0627\u0631\u06cc\u0648\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0645\u0648\u062c\u0648\u062f \u062f\u0631 \u0645\u0637\u0627\u0644\u0639\u0627\u062aHarmony \u0628\u0631\u0631\u0648\u06cc \u0648\u0642\u0644\u0648 \u0647\u0627<\/p>\n

    \n
  • \u062f\u0648\u0642\u0644\u0648\u0647\u0627\u06cc \u062a\u06a9 \u06a9\u0648\u0631\u06cc\u0648\u0646\u06cc\u06a9<\/li>\n
  • \u062f\u0648\u0642\u0644\u0648\u0647\u0627\u06cc \u062f\u06cc \u06a9\u0648\u0631\u06cc\u0648\u0646\u06cc<\/li>\n
  • \u062f\u0648\u0642\u0644\u0648\u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0628\u0627\u00a0\u0644\u0642\u0627\u062d<\/i>\u00a0\u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc (IVF) \u0628\u0647 \u0648\u062c\u0648\u062f \u0622\u0645\u062f\u0647 \u0627\u0646\u062f.<\/li>\n
  • \u062f\u0648\u0642\u0644\u0648\u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0628\u0647 \u0637\u0648\u0631 \u0637\u0628\u06cc\u0639\u06cc \u0628\u0647 \u062f\u0646\u06cc\u0627 \u0622\u0645\u062f\u0647 \u0627\u0646\u062f .<\/li>\n
  • \u0628\u0627\u0631\u062f\u0627\u0631\u06cc \u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0647\u0631 \u062f\u0648 \u062f\u0648\u0642\u0644\u0648 \u0622\u0646\u06cc\u0648\u067e\u0644\u0648\u0626\u06cc\u062f\u06cc \u062f\u0627\u0631\u0646\u062f.<\/li>\n
  • \u0628\u0627\u0631\u062f\u0627\u0631\u06cc \u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0641\u0642\u0637 \u06cc\u06a9\u06cc \u0627\u0632 \u062f\u0648\u0642\u0644\u0648 \u0647\u0627 \u0622\u0646\u06cc\u0648\u067e\u0644\u0648\u0626\u06cc\u062f\u06cc \u062f\u0627\u0631\u062f.<\/li>\n
  • \u062a\u0633\u062a \u0633\u0647 \u0645\u0627\u0647\u0647 \u0627\u0648\u0644<\/li>\n
  • \u062a\u0633\u062a \u0633\u0647 \u0645\u0627\u0647\u0647 \u062f\u0648\u0645<\/li>\n<\/ul>\n
    \n

    \u0627\u0646\u062c\u0645\u0646\u200c\u0647\u0627\u06cc\u06cc \u0645\u0627\u0646\u0646\u062f \u0627\u0646\u062c\u0645\u0646 \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc \u062a\u0634\u062e\u06cc\u0635 \u067e\u06cc\u0634 \u0627\u0632 \u062a\u0648\u0644\u062f (ISPD) \u0648 \u06a9\u0627\u0644\u062c \u0622\u0645\u0631\u06cc\u06a9\u0627\u06cc\u06cc \u0698\u0646\u062a\u06cc\u06a9 \u067e\u0632\u0634\u06a9\u06cc \u0648 \u0698\u0646\u0648\u0645\u06cc\u06a9 (ACMG) \u0627\u0632 \u0627\u0631\u0627\u0626\u0647 NIPT \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u062e\u0637 \u0627\u0648\u0644 \u063a\u0631\u0628\u0627\u0644\u06af\u0631\u06cc \u062d\u0645\u0627\u06cc\u062a \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f.<\/p>\n

    \u067e\u0631\u0648\u062a\u06a9\u0644 \u0647\u0627\u06cc \u0632\u06cc\u0631 \u062f\u0631 \u062d\u0627\u0644 \u062d\u0627\u0636\u0631 \u067e\u06cc\u0634\u0645\u0647\u0627\u062f \u0645\u06cc\u0634\u0648\u0646\u062f : \u063a\u0631\u0628\u0627\u0644\u06af\u0631\u06cc cfDNA \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u06cc\u06a9 \u0622\u0632\u0645\u0627\u06cc\u0634 \u0627\u0648\u0644\u06cc\u0647 \u06a9\u0647 \u0628\u0631\u0627\u06cc \u0647\u0645\u0647 \u0632\u0646\u0627\u0646 \u0628\u0627\u0631\u062f\u0627\u0631 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc \u0634\u0648\u062f.17<\/sup><\/b><\/p>\n

    ACMG \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f \u0628\u0647 \u0647\u0645\u0647 \u0632\u0646\u0627\u0646 \u0628\u0627\u0631\u062f\u0627\u0631 \u0627\u0637\u0644\u0627\u0639 \u062f\u0647\u06cc\u062f \u06a9\u0647 NIPS\u062f\u0642\u06cc\u0642 \u062a\u0631\u06cc\u0646 \u06af\u0632\u06cc\u0646\u0647 \u063a\u0631\u0628\u0627\u0644\u06af\u0631\u06cc \u0628\u0631\u0627\u06cc \u062a\u0631\u06cc\u0632\u0648\u0645\u06cc 21\u060c \u062a\u0631\u06cc\u0632\u0648\u0645\u06cc 18 \u0648 \u062a\u0631\u06cc\u0632\u0648\u0645\u06cc 13 \u0627\u0633\u062a.18<\/sup><\/b><\/p>\n\n\t\t<\/div>\n\t<\/div>\n\n\t

    \n\t\t
    \n\t\t\t

    \u0645\u0646\u0627\u0628\u0639<\/h3>\n
      \n
    1. Norton et al. New Engl J of Med. 2015; 372(17):1589-1597.<\/li>\n
    2. Norton et al. Am J Obstet Gynecol.2012 Aug;207(2):137-8.<\/li>\n
    3. Stokowski et al. Prenat Diagn. 2015 Dec;35(12):1243-6.<\/li>\n
    4. Schmid et al. Fetal Diagn Ther 2017; Doi:10.1159\/000484317.<\/li>\n
    5. Grati et al. Prenat Diagn 2015;35:801-809.<\/li>\n
    6. Wapner et al. N Engl J Med 012;367:2175-2184.<\/li>\n
    7. McDonald-McGinn et al. Gnet Med.2001 Jan-Feb:3(1):23-9.<\/li>\n
    8. Bassett et al. JPediatr. 2011 Aug;159(2):332-9.<\/li>\n
    9. Thompson and Thompson. Genetics in Medicine, Sixth Edition. Robert L Nussbaum, Roderick Mclnnes, Willard Huntington, Saunders, 2001.<\/li>\n
    10. del Mar Gil M, et al. Fetal Diagn Ther. 2014;35(3):204-211.<\/li>\n
    11. Struble C et al. Fetal Diagn Ther. 2013;35(3):199-203.<\/li>\n
    12. Bevilacqua E, et al. Ultrasound Obstet Gynecol. 2015;45(1):61-66.<\/li>\n
    13. Stokowski et al. Prenat Diagn. 2015 Dec;35(12):1243-6.<\/li>\n
    14. Sarno L, et al. Ultrasound Obstet Gynecol. 2016;47(6):705-711.<\/li>\n
    15. Jones KJ, et al. Obstet Gynecol. 2018 51:274-277.<\/li>\n
    16. Data on file.<\/li>\n
    17. Benn et al. Prenat Diagn 2015; 35: 725\u2013734.<\/li>\n
    18. Gregg et al. Genetics in Medicine 2016 Oct; 18(10):1056-65.<\/li>\n<\/ol>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"Exceptional performance in the general population The Harmony test outperformed traditional first-trimester screening (FTS) in a landmark study (NEXT) published in the New England Journal of Medicine.2 In this prospective blinded study, the Harmony test was found to be superior to FTS in terms of detection rate, false positive rate and positive predictive value for [...]","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7649","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/pages\/7649","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/comments?post=7649"}],"version-history":[{"count":6,"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/pages\/7649\/revisions"}],"predecessor-version":[{"id":7874,"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/pages\/7649\/revisions\/7874"}],"wp:attachment":[{"href":"https:\/\/harmonipt.com\/fa\/wp-json\/wp\/v2\/media?parent=7649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}